Phago-FERSISI Bacteriophage

Composition:

Phago-Fersisi bacteriophage is a sterile filtrate of phage lysates active to:
• Staphylococcus;
• Streptococcus;
Inactive ingredients: Bacteriological growth medium, standard sodium saline. Chinazolin as a preservative.

Description:

The solution is transparent liquid, with a yellow to light brown colour.

Pharmacological actions:

Phago-Fersisi Bacteriophage leads to specific lysis of bacteria belonging to Staphylococci and Streptococci.

Recommendations for use:

Phago-FERSISI bacteriophage is a paratherapeutic product. It can be used during pyo-inflammatory and enteric infections caused by the above-mentioned microorganisms, including prophylactic purposes.
Indications: Otolaryngological diseases: inflammation of the middle ear, tonsillitis, laryngitis, rhinitis, tracheitis, bronchitis, pneumonia, pleurisy.
Skin infections: furunculosis, carbunculosis, abscess, deep infiltration and abscessing sycosis. Surgical infections: abscess, wound infections, mastitis, osteomyelitis, phlegmon. Inflammation of oral cavity: stomatitis, gingivitis, etc. Eye diseases: bacterial conjunctivitis. Secondary infections with thermal burns. Urogenetal and gynecologic infections: urethritis, cystitis, pyelonephritis, endometritis. Enteric infections: gastroenterocolitis, cholecystitis, staphylococcal toxic infection, dysbacterioses. Pyo-inflam- matory disease in children (including newborns). Prevention of postoperative periods and hospital infection.

Usage and dosage:

Used as a processing site lesions topically (as tampon), and for the introduction into the cavity (bladder, pleural and peritoneal cavity, nasal cavity, deep wounds, abscesses, uterus, and vagina). The solution is also recommended for use due to enemas, tubing and drainage.
When applied topically, the duration of application does not exceed 3 -8 days, 3 times a day. The amount of the solution to be applied is defined according to the size of the affected area, it varies from 50 to 200 ml. Application can start only after cleaning the wound or cavity from the pus. In cystitis, pyelitis phage can be introduced by a catheter. In cholecystitis, phage is given through the tube 30 ml, once every 2 days. In case of conjunctivitis, phage is applied in the eye 4 - 6 times a day, 2 -3 drops. In newborns with pyoderma phage used with sterile napkins, two times a day. Usage lasts from 5 to 7 days. Before the use of phage per os drinking a 2-3% solution of baking soda(one glass, 150-200ml) is recommended to reduce stomach acid.

Special Warnings:

Before use, the vial should be well shaken. The contents should be transparent liquid without sediment. The solution should not be used in case of vial damage or if the liquid inside is non-transparent! Do not store and use the solution after destroying the integrity of the vial!!!

Overdosing, contradictions and side effects :
During the usage of Phago-FERSISI bacteriophage, overdosing symptoms have not been revealed. Usage of Phago-FERSISI bacteriophage does not have contradictions.
No side effects have been revealed during usage of Phago-FERSISI bacteriophage.

Usage together with other preparations:

Phago-FERSISI can be used in parallel or supplemental to other medications. Drinking alcohol during use of bacteriophages is not recommended.

Specific categories of patients:
Pregnancy and lactation:

Bacteriophages can be used during pregnancy and the lactation period.

Usage in elderly people:

Bacteriophages are used in elderly people.

Effect on drivers and people working with potentially harmful machines:

Usage of bacteriophages does not affect driving skills or the skills of other equipment usage.

Packaging:

Phago-FERSISI bacteriophage is produced in 10 ml vials (5 vials per pack).

Storage conditions and shelf life:

Store at +2C - +8C in a dry place, protected from direct light. Shelf life is 24 months.

Issued without prescription

Developed by G. Eliava Institute of Bacteriophages, Microbiology and Virology

Phago-FERSISI is a paratherapeutic product and doesn’t include GMO.

Manufactured by:

“Eliava Biopreparations” LLC
3, Gotua str. Tbilisi, 0160, Georgia Phone: +995 (32) 2370702
E-mail: info@phage.ge

You can download the following materials:

Instruction for Use 
Material Safety Data Sheet (MSDS)

Phago-Staph Bacteriophage

Composition:

Phago-Staph bacteriophage is a filtrate of the purified phage lysate active against Staphylococcus aureus strains.
Inactive ingredients: Bacteriological growth medium, standard sodium saline. Chinazolin as a preservative.

Description:

Preparation is transparent, colorless liquid.

Pharmacological actions:

Phago-Staph bacteriophage leads to a specific lysis of bacteria belonging to the Staphylococcus aureus spices.

Recomendations for use:

Phago-Staph bacteriophage is a paratherapeutic product. It can be used during infections caused by Staphylococcal bacteria and for prophylaxis.
Indications:
Phago-Staph is directed to use during infections caused by Staphylococcus aureus such as:

•Upper airways, nose, throat, lung, ear (pharyngitis, tonsillitis, tracheitis, bronchitis, pleuritis, pneumo- nia, inflammation of middle ear) infectious diseases;
•Surgical infections (infectious wound, infected burn, abscess, phlegmon, furuncle, carbuncle, paraproc- titis, mastitis, bursitis, osteomyelitis, panaricium);

•Urogenital infections (urethritis, cystitis, pyelonephritis, colpitis, endometritis);
•Enteric infections (gastroenteric colitis, cholecystitis);
•Purulent-septic infections in newborn (omphalitis, pyoderma, conjunctivitis, gastroenteric colitis and others)
•Other Staphylococcal infections

Usage and dosage:

Phago-Staph bacteriophage is used for prophylaxis and during post-operational and infected wounds, as well as hospital staphylococcal infections, confirmed as an epidemiological indicator.
Phago-Staph can be used through different applications, including: per os, treatment of wounds by drainage and application, per rectum, through applications directly inside the ear, throat, nose, urinary tract cavities.

Recommended doses of Phago-Staph bacteriophage are as follows:

During Per os application of Phago-Staph bacteriophage in adults and children from age of 3, drinking of 2-3% baking soda solution (one glass, 150-200 ml) is recommended.

n case of infectious abscess, phage is introduced by injection in abscess cavity after evacuation of pus; the volume of used phage should be less than evacuated pus. In case of open abscess, tampon with phage might be used in cavity. In case of lung abscess, phage is used by trans-thoracal puncture and by catheter in tracheobronchial system. In case of emphysema, solution could be used by puncture and drainage. One dose includes 10-20ml of phage during phage application by catheter of tracheo- broncheal system, in case of emphysema – the single dose is from 10 ml to 50 ml.

Special Warnings:

Before use, the vial should be well shaken. The contents should be transparent liquid without sediment. The solution should not be used in case of vials damage or if the liquid inside is non-trans- parent! Do not store and use the solution after destroying the integrity of the vial!!!

Overdosing, contradictions and side effects :

During the usage of Phago-Staph bacteriophage, overdosing symptoms have not been revealed. Usage of Phago-Staph bacteriophage does not have contradictions.
No side effects have been revealed during usage of Phago-Staph bacteriophage.

Usage together with other preparations:

Phago-Staph can be used in parallel or supplemental to other medications. Drinking alcohol during use of bacteriophages is not recommended.

Specific categories of patients:
Pregnancy and lactation:

Bacteriophages can be used during pregnancy and lactation period.

Usage in elderly people:

Bacteriophages are used in elderly people.

Effect on drivers and people working with potentially harmful machines:

Usage of bacteriophages does not affect driving skills or skills of other equipment usage.

Packaging:

Phago-Staph bacteriophage is produced in 10 ml vials (5 vials per pack).

Storage conditions and shelf life:

Store at +2C - +8C in dry place, protected from direct light.

Shelf life 24 month.

Issued without prescription

Developed by G. Eliava Institute of Bacteriophages, Microbiology and Virology

Phago-Staph is a paratherapeutic product and doesn’t include GMO

Manufactured by:

“Eliava Biopreparations” LLC
3, Gotua str. Tbilisi, 0160, Georgia Phone: +(995)32 2370702
E-mail: info@phage.ge

You can download the following materials:

Instruction for Use
Material Safety Data Sheet (MSDS)

Phago-Pyo

Composition:

Phago-Pyo bacteriophage is a combined solution which is a mix of sterile filtrates of phage lysates active to:
• Staphylococcus,
• Streptococcus ,

• Different types of E. coli ,
• Pseudomonas aeruginosa,
• Proteus,
Inactive ingredients: Bacteriological growth medium, standard sodium saline. Chinazolin as preservative

Description:

Solution is transparent liquid, with yellow to light brown colour.

Pharmacological actions:

Phago-Pyo bacteriophage leads to a specific lysis of bacteria belonging to: Staphylococcus, Streptococ- cus, E.coli (Different serotypes), Pseudomonas aeruginosa, Proteus species.

Recomendations for use:

Phago-Pyo bacteriophage is a paratherapeutic product. It can be used during purulent inflammatory and enteric infectious diseases caused by above enlisted microorganisms.
Indications:
•Otorhinolaryngeal and respiratory bacterial infections including: rhinitis, otitis, paranasal sinusitis, pyogenic tonsillitis, pharyngitis, laryngitis, tracheitis, bronchitis, pneumonia, pleuritic;

•Dermatological bacterial infections including: pyoderma, abscesses, furunculi and carbuncles, hydradentitis;
•Surgical site bacterial infections including: infectious wounds, mastitis, flegms;
•Oral bacterial infections including: stomatitis, gingivitis, periodontitis and other;

•Ocular bacterial infections, including: conjunctivitis, blepharitis;
•Burn wounds with secondary bacterial infections
•Urogenital and gynecological infections: Urethritis, cystitis, pyelonephritis, colpitis, endometritis; •Gastrointestinal bacterial infections including: gastroenterocolitis, dysbacteriosis (bacterial overgrowth syndrome), paraproctitis;
•Omphalitis of newborn, purulent septic infections in children (including newborn);
•Infectious diseases lead by Staphylococcus, Streptococcus, E. coli (Different serotypes), Pseudomonas aeruginosa, Proteus bacteria;
•Prophylactic purposes against post-operational complications and hospital infections;

Usage and dosage:

Optimal results are achieved when Phago-Pyo bacteriophage is used at the onset of infection and when introduced directly to the infection site. Phago-Pyo bacteriophage is used as a disinfecting agent by phage soaked bandages applied directly into a cavity (wound, including abscess, abdominal, pleural, nasal, urinary bladder, uterine, vaginal) The solution may be used orally per os, and/or by urinary catheter or rectally per rectum via enema.
- Local application of Phago-Pyo bacteriophage is performed daily during 3-5 day period, three times a day. Amount of the solution is determined by the size of the affected area. If various chemical antiseptics were used to treat the wound before phage application, it should be cleaned by sterile saline solution and 2-3% soda solution should be applied.
- For use during abscesses, pleuritis, arthritis, and peritonitis, 50-200ml of Phago-Pyo bacteriophage may be instilled directly into the cavity, every other day. (Exact amount of applied phage is determined based on the size of cavity) Before instillation of bacteriophages, pus from cavities should be extract- ed.
- During cystitis and pyelonephritis Phago- Pyo bacteriophage may be administered via urinary catheter or per os;
- During cholecystitis, Phago- Pyo bacteriophage can be applied through intubation with amount of 30 ml every other day.
- In case of stomach surgery or peritonitis, 100ml phage is applied in cavity, daily during 3-4 days. In case of application through catheter 30ml phage is applied daily during 3-4 days.
- For use during deep forms of pyoderma. Intradermal injection may be used (0.1-0.5 ml per injection) up to maximum of 10 injections during 24 hours.
- For conjunctivitis, Phago-Pyo bacteriophage is instilled via pipette, 2 drops in each eye, 4-6 times daily during 3-5 days.
- In cases of neonatal omphalitis and pyoderma, application is by Phage soaked bandage twice daily for 5-7 days.

During Per os application of Phago-Pyo bacteriophage in adults and children from age of 3, drinking of 2-3% baking soda solution (one glass, 150-200 ml) is recommended.

Special Warnings:

Before use, the vial should be well shaken. The contents should be transparent liquid without sediment. The solution should not be used in case of vials damage or if the liquid inside is non-trans- parent! Do not store and use the solution after destroying the integrity of the vial!!!

Overdosing, contradictions and side effects :

During the usage of Phago-Pyo bacteriophage, overdosing symptoms have not been revealed.
Usage of Phago-Pyo bacteriophage does not have contradictions.
No side effects have been revealed during usage of Phago-Pyo bacteriophage.

Usage together with other preparations:

Phago-Pyo can be used in parallel or supplemental to other medications. Drinking alcohol during use of bacteriophages is not recommended.

Specific categories of customers:
Pregnancy and lactation:

Bacteriophages can be used during pregnancy and lactation period.

Usage in elderly people:

Bacteriophages are used in elderly people.

Effect on drivers and people working with potentially harmful machines:

Usage of bacteriophages does not affect driving skills or skills of other equipment usage.

Packaging:

Phago-Pyo bacteriophage is produced in 10 ml vials (5 vials per pack).

Storage conditions and shelf life:

Store at +2C - +8C in dry place, protected from direct light. Shelf life 24 month.

Issued without prescription

Preparation developed by G. Eliava Institute of Bacteriophages, Microbiology and Virology

Phago-Pyo is a paratherapeutic product and doesn’t include GMO.

Manufactured by:

“Eliava Biopreparations” LLC
3, Gotua str. Tbilisi, 0160, Georgia Phone: +(995)32 2370702
E-mail: info@phage.ge

You can download the following materials:

Instruction for use
Material Safety Data Sheet (MSDS)

Phago-Intesti Bacteriophage

Composition:

Phago-Intesti bacteriophage is a combined solution. Phago-Intesti bacteriophage is a mix of sterile filtrates of phage lysates active to:
• Shigella,
• Salmonella,

• Different types of E. coli,
• Proteus,
• Staphylococcus,
• Pseudomonas aeruginosa,

• Enterococcus,

Inactive ingredients: Bacteriological growth medium, standard sodium saline. Chinazolin as preserva- tive.

Description:

Solution is a transparent liquid, with yellow to light brown colour.

Pharmacological actions:

Phago-Intesti bacteriophage leads to specific lysis of following bacteria: Shigella; Salmonella; Esche- richia coli; Proteus; Staphylococcus; Pseudomonas aeruginosa; Enterococcus.

Recomendations for use:

Phago-Intesti bacteriophage is a paratherapeutic product. It can be used during intestinal infectious diseases caused by enlisted microorganisms and for the prophylaxis.
Indications:

- Dysentery;

- Salmonellosis;

- Dyspepsia.;
- Infective colitis;

- Enterocolitis;

- Dysbiosis;

Usage and dosage:

Phago-Intesti bacteriophage can be used per os with first signs of disease within 5-6 days. Phago-In- testi bacteriophage should be used in following doses:

During Per os application of Phago- Intesti bacteriophage in adults and children from age of 3, drinking of 2-3% baking soda solution (one glass, 150-250 ml) is recommended.

In parallel to per os admission of Phago-Intest ibacteriophage it is recommended to use it per rectum, once a day in the amount of 10 ml for children and 20 ml for adults. (Per rectum usage is recommend- ed in the evening with enema after empting stomach)
For prophylaxis use Phago-Intesti bacteriophage is recommended:

- In organized groups to prevent spread of infections. During seasonal infections, Phago-Intesti bacteriophage can be applied once a day in amount of 10-20 ml. Application can be made with the interval of 5 days during 1 month.
- During the increase cases of intestinal infections, all patients in the clinics are recommended to go through phage treatment despite diagnoses. Phage application is recommended 2 times with the interval of 5 days. Amount per admission should be 10-20 ml.

Special Warnings:

Before use, the vial should be well shaken. The contents should be transparent liquid without sediment. The solution should not be used in case of vials damage or if the liquid inside is non-trans- parent! Do not store and use the solution after destroying the integrity of the vial!!!

Overdosing, contradictions and side effects :

During the usage of Phago-Intesti bacteriophage, overdosing symptoms have not been revealed. Usage of Phago-Intesti bacteriophage does not have contradictions.
No side effects have been revealed during usage of Phago-Intesti bacteriophage.

Usage together with other preparations:

Phago-Intesti can be used in parallel or supplemental to other medications. Drinking alcohol during use of bacteriophages is not recommended.

Specific categories of patients:
Pregnancy and lactation:

Phago-Intesti can be used during pregnancy and lactation period.

Usage in elderly people:

Phago-Intesti is used in elderly people.

Effect on drivers and people working with potentially harmful machines:

Usage of bacteriophages does not affect driving skills or skills of other equipment usage.

Packaging:

Phago-Intesti bacteriophage is produced in 10 ml vials (5 vials per pack).

Storage conditions and shelf life:

Store at +2C - +8C in dry place, protected from direct light. Shelf life 24 month.

Issued without prescription

Developed by G. Eliava Institute of Bacteriophages, Microbiology and Virology.

Phago-Intesti is a paratherapeutic product and doesn’t include GMO.

“Eliava Biopreparations” LLC
3, Gotua str. Tbilisi, 0160, Georgia Phone: +(995)32 2370702
E-mail: info@phage.ge

You can download the following materials: 

Instruction for Use

Material Safety Data Sheet (MSDS)

Phago-SES Bacteriophage

Composition:

Phago-SES bacteriophage is a sterile filtrate of phage lysates active to:

• Staphylococcus;
• Streptococcus;
• E.coli;

Inactive ingredients: Bacteriological growth medium, standard sodium saline; Chinazolin as a preservative.

Description:

Preparation is transparent liquid, with yellow to light brown colour.

Pharmacological actions:

Phago-SES Bacteriophage leads to a specific lysis of bacteria belonging to Staphylococci, Streptococci and Enteropathogenic E. coli of different serovars.

Recomendations for use:

Phago-SES bacteriophage is a paratherapeutic product. It can be used during pyo-inflammatory and enteric infections caused by the above-mentioned microorganisms including prophylactic purposes.
Indications:

Otolaryngological diseases: Otitis, tonsillitis, laryngitis, rhinitis, tracheitis, bronchitis, pneumonia, pleurisy. Skin infections: furunculosis, carbunculosis, deep infiltration and abscessing sycosis. Surgical infections: abscess, wound infections, mastitis, osteomyelitis, phlegmon. Inflammation of oral cavity: stomatitis, gingivitis, etc. Eye diseases: bacterial conjunctivitis. Secondary infections with thermal burns. Urogenetal and gynecologic infections: urethritis, cystitis, pyelonephritis, endometritis. Enteric infections: gastroenterocolitis, cholecystitis, staphylococcal toxic infection, dysbacterioses. Pyo-inflam- matory disease in children (including newborns). Prevention of postoperative periods and hospital infection.

Usage and dosage:

Used during lesions locally (as tampon), and for injecting into the cavity (bladder, pleural and peritoneal cavity, nasal cavity, deep wounds, abscesses, uterus and vagina). The solution is also recommended for using by enemas, and injecting through a tube and drainage. When applied locally, duration of aplication does not exceed 3 -8 days, 3 times a day. The amount of the Phago-SES to be applied is defined according to the size of the affected area, it varies from 50 to 200 ml. Application can start only after cleaning the wound or cavity from the pus. In case of cystitis and pyelitis the phage can be applied by catheter. In case of cholecystitis 30 ml of phage is used through the tube, once in every 2 days. In case of conjunctivitis the phage is applied in the eye 4 - 6 times a day, 2 - 3 drops. In newborns with pyoderma the phage is used with sterile napkins, 2 times a day. Usage lasts from 5 to 7 days. Before taking the phage per os drinking a 2-3% solution of baking soda(one glass, 150-200ml) is recommended to reduce stomach acid.

Special Warnings:

Before use, the vial should be well shaken. The contents should be transparent liquid without sediment. The solution should not be used in case of vials damage or if the liquid inside is non-trans- parent! Do not store and use the solution after destroying the integrity of the vial!!!

Overdosing, contradictions and side effects :

During the usage of Phago-SES bacteriophage, overdosing symptoms have not been revealed. Usage of Phago-SES bacteriophage does not have contradictions.
No side effects have been revealed during usage of Phago-SES bacteriophage.

Usage together with other preparations:

Phago-SES can be used in parallel or supplemental to other medications. Drinking alcohol during use of bacteriophages is not recommended.

Specific categories of patients:
Pregnancy and lactation:

Bacteriophages can be used during pregnancy and lactation period.

Usage in elderly people:

Bacteriophages are used in elderly people.

Effect on drivers and people working with potentially harmful machines:

Usage of bacteriophages does not affect driving skills or skills of other equipment usage.

Packaging:

Phago-SES bacteriophage is produced in 10 ml vials (5 vials per pack).

Storage conditions and shelf life:

Store at +2C - +8C in dry place, protected from direct light. Shelf life 24 month.

Issued without prescription

Developed by G. Eliava Institute of Bacteriophages, Microbiology and Virology

Phago-SES is a paratherapeutic product and doesn’t include GMO.

Manufactured by:

“Eliava Biopreparations” LLC
3, Gotua str. Tbilisi, 0160, Georgia Phone: +995 (32) 2370702
E-mail: info@phage.ge

You can download the following materials:

Instruction for Use 
Material Safety Data Sheet (MSDS)

Composition:

Phago-ENKO Bacteriophage

Composition:

Phago-Enko bacteriophage is a sterile filtrate of phage lysates active to:

• Shigella;
• Salmonella;
• Different types of E. coli;

• Species of pathogenic Staphylococcus;
Inactive ingredients: Bacteriological growth medium, standard saline solution. Chinazolin as a preservative.

Description:

Preparation is transparent liquid, with yellow to light brown colour.

Pharmacological actions:

Phago-Enko Bacteriophage leads to a specific lysis of bacteria belonging to Staphylococcus, Shigella, E.coli and Salmonella of different serovars.

Recomendations for use:

Phago-ENKO bacteriophage is a paratherapeutic product. It can be used during enteric infections caused by the above-mentioned microorganisms as well as for prophylactic purposes.
Indications:
Enteric infections: dysentery, salmonellosis, dyspepsia, colitis, gastro enterocolitis, cholecystitis, staphylococcal toxic infection, disbiosis etc.

Usage and dosage:

Phago-Enko phage can be used per os from the first days of the disease for 5 - 6 days in the following doses:
• Children under 3 years - 5ml per reception,
• Children above 3 years old and adolescents - 10 ml at once, 4 times a day, 30 minutes before the meal.

Before taking the phage per os, taking 2-3% solution of baking soda (one glass, 150-200 ml) is recom- mended to reduce stomach acid.
During infectious intestinal diseases, the solution is given in combination with applying the phage by enemas; preferably, in the evening time once a day, after a cleansing enema with a baking soda solution, per rectum: 10 ml of the preparation for children and 20 ml - for adults.

During outbreak of infectious intestinal diseases, the solution is given to all patients, regardless of clinical diagnosis, 10-20 ml twice a day, for five days.

Special Warnings:

Before use, the vial should be well shaken. The contents should be transparent liquid without sediment. The solution should not be used in case of vials damage or if the liquid inside is non-trans- parent! Do not store and use the solution after destroying the integrity of the vial!!!

Usage together with other preparations:

Phago-ENKO can be used in parallel or supplemental to other medications. Drinking alcohol during use of bacteriophages is not recommended.

Specific categories of patients:
Pregnancy and lactation:

Bacteriophages can be used during pregnancy and lactation period.

Usage in elderly people:

Bacteriophages can be used in elderly people.

Effect on drivers and people working with potentially harmful machines:

Usage of bacteriophages does not affect driving skills or skills of other equipment usage.

Packaging:

Phago-ENKO bacteriophage is produced in 10 ml vials (5 vials per pack).

Storage conditions and shelf life:

Store at +2C - +8C in dry place, protected from direct light. Shelf life 24 months.

Issued without prescription

Phago-ENKO is a paratherapheutic product and doesn’t include GMO.

Manufactured by:

“Eliava Biopreparations” LLC
3, Gotua str. Tbilisi, 0160, Georgia Phone: +995 (32) 2370702
E-mail: info@phage.ge

You can download the following materials:

Instruction For Use
Material Safety Data Sheet (MSDS)